Biology – Page 5
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ResearchPainting with DNA
Fluorescently labeled DNA strands produce a palette of 16 million colours
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ResearchControlling insulin activity in cells with ‘DNA origami’
Insulin–DNA nanorods elicit geometry-dependent insulin activity, which could lead to more targeted treatments for diabetes
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FeatureBattling long Covid with drugs
The challenge of finding drugs for a poorly understood disease with many symptoms is clear. Clare Sansom looks at the work going on to help the people suffering in its shadow
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ResearchACE2 receptor not essential for Sars-CoV-2 infection, study shows
Fresh understanding linked to evolutionary plasticity of Covid-19 virus
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ResearchField study reveals banned pesticide sulfoxaflor had no effect on pollination by bumblebees
Work adds to nuanced picture of pesticide’s effect on pollinating insects
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FeatureMedical uses for silk
Nina Notman speaks to the researchers exploring medical applications for silkworm silk
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ResearchDirect imaging reveals individual protein-bound glycans in new detail
Sequences and locations of biomolecule-bound sugar chains studied at the single-molecule level
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ResearchGenetic-editing of chickens protects them from catching the flu
Approach heralds new way to make animals resistant to disease
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OpinionWill the assembly theory imbroglio do anything for evolution?
A claim to have explained selection has caused a stir, and it’s worth asking why, says Philip Ball
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ResearchAssembly theory puts chemistry centre stage to explain molecular complexity and life’s origins
Concept that attempts to join physics and biology via chemistry met with interest but also harsh criticism
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OpinionMoving beyond protein structure
Efforts to understand how intrinsically disordered regions interact have produced a variety of answers
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ResearchMutation studies reveal how Antarctic octopus arms itself with cool enzyme
Understanding cold-tolerant enzyme could help with transplant organ preservation
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ResearchCryo-EM scaffold supports imaging of small proteins previously tricky to study
Improved understanding of the structure of small proteins could aid drug designers
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NewsmRNA vaccine pioneers win medicine Nobel prize
Katalin Karikó and Drew Weissman honoured for breakthroughs that enable the rapid development of new vaccines, including several of those used against Covid-19
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Research’This is just the beginning’: RNA editing set to democratise viral engineering
Crispr-based system could ease development of novel RNA therapies
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FeatureUsing DNA evidence to picture suspects
Forensic DNA phenotyping predicts people’s appearance and reveals their ancestry, finds Andy Extance, but has some significant challenges to overcome
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BusinessTornado at Pfizer plant accentuates US drug shortage issues
Perennial problem will not be addressed without major reforms to drug market
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ResearchSnail study unveils composition of three different types of mucus
Findings could help develop synthetic mucus for biomedical applications, as well as cosmetics
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ResearchChemical industry hasn’t yet developed an appetite for biocatalysis, survey finds
Misconceptions along with a lack of time and resources driving industry’s reluctant attitude to biocatalysis and chemoenzymatic catalysis